5,6-MeO-MiPT

5,6-MeO-MiPT
Clinical data
Other names	5,6-Dimethoxy-N-methyl-N-isopropyltryptamine
Routes of; administration	Oral
Drug class	Serotonin receptor modulator
ATC code	None;
Pharmacokinetic data
Onset of action	Unknown
Duration of action	Unknown
Identifiers
	IUPAC name N-[2-(5,6-dimethoxy-1H-indol-3-yl)ethyl]-N-methylpropan-2-amine;
CAS Number	96096-58-1 ;
PubChem CID	44382345;
ChemSpider	23511916;
UNII	BS78RK38CG;
ChEMBL	ChEMBL172460;
CompTox Dashboard (EPA)	DTXSID501336586 ;
Chemical and physical data
Formula	C16H24N2O2
Molar mass	276.380 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N(C)CCc2c[nH]c1cc(OC)c(OC)cc12;
	InChI InChI=1S/C16H24N2O2/c1-11(2)18(3)7-6-12-10-17-14-9-16(20-5)15(19-4)8-13(12)14/h8-11,17H,6-7H2,1-5H3; Key:XXWWFLAMFUOAQG-UHFFFAOYSA-N;

5,6-MeO-MiPT, also known as 5,6-dimethoxy-N-methyl-N-isopropyltryptamine, is a chemical compound of the tryptamine family.^[1] It is the 5,6-dimethoxy derivative of methylisopropyltryptamine (MiPT) and is an analogue of 5-MeO-MiPT.^[1] In his 1991 book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin listed the dose as greater than 75 mg orally and the duration as unknown.^[1] The drug produced few to no effects at doses of up to 75 mg orally.^[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of 5,6-MeO-MiPT.^[1] However, the drug has been found to have abolished or profoundly reduced affinities for serotonin receptors compared to psychedelic tryptamines like MiPT and 5-MeO-MiPT.^[2] Its chemical synthesis has been described.^[1] 5,6-MeO-MiPT was first described in the scientific literature by David Repke and Alexander Shulgin and colleagues.^[3]

References

1 2 3 4 5 6 7 8 9 Shulgin, Alexander; Shulgin, Ann (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
↑ McKenna DJ, Repke DB, Lo L, Peroutka SJ (March 1990). "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology. 29 (3): 193–198. doi:10.1016/0028-3908(90)90001-8. PMID 2139186.
↑ Repke DB, Grotjahn DB, Shulgin AT (July 1985). "Psychotomimetic N-methyl-N-isopropyltryptamines. Effects of variation of aromatic oxygen substituents". J Med Chem. 28 (7): 892–896. doi:10.1021/jm00145a007. PMID 4009612.

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Clinical data


Other names	5,6-Dimethoxy-N-methyl-N-isopropyltryptamine
Routes of administration	Oral^[1]
Drug class	Serotonin receptor modulator
ATC code	None
Pharmacokinetic data
Onset of action	Unknown^[1]
Duration of action	Unknown^[1]
Identifiers
IUPAC name N-[2-(5,6-dimethoxy-1H-indol-3-yl)ethyl]-N-methylpropan-2-amine
CAS Number	96096-58-1^Y
PubChem CID	44382345
ChemSpider	23511916
UNII	BS78RK38CG
ChEMBL	ChEMBL172460
CompTox Dashboard (EPA)	DTXSID501336586
Chemical and physical data
Formula	C₁₆H₂₄N₂O₂
Molar mass	276.380 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)N(C)CCc2c[nH]c1cc(OC)c(OC)cc12
InChI InChI=1S/C16H24N2O2/c1-11(2)18(3)7-6-12-10-17-14-9-16(20-5)15(19-4)8-13(12)14/h8-11,17H,6-7H2,1-5H3 Key:XXWWFLAMFUOAQG-UHFFFAOYSA-N