Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Jan 11;25(2):928.
doi: 10.3390/ijms25020928.

Advances in the Regulation of Neural Function by Infrared Light

Affiliations
Review

Advances in the Regulation of Neural Function by Infrared Light

Lequan Song et al. Int J Mol Sci. .

Abstract

In recent years, with the rapid development of optical technology, infrared light has been increasingly used in biomedical fields. Research has shown that infrared light could play roles in light stimulation and biological regulation. Infrared light has been used to regulate neural function due to its high spatial resolution, safety and neural sensitivity and has been considered a useful method to replace traditional neural regulation approaches. Infrared neuromodulation methods have been used for neural activation, central nervous system disorder treatment and cognitive enhancement. Research on the regulation of neural function by infrared light stimulation began only recently, and the underlying mechanism remains unclear. This article reviews the characteristics of infrared light, the advantages and disadvantages of infrared neuromodulation, its effects on improving individual health, and its mechanism. This article aims to provide a reference for future research on the use of infrared neural regulation to treat neuropsychological disorders.

Keywords: infrared light; mechanism; nerve function; regulation.

PubMed Disclaimer

Conflict of interest statement

All authors have reviewed the manuscript, and they have no competing financial interests or personal relationships that might have influenced the work reported here.

Figures

Figure 1
Figure 1
IR light could improve the symptoms of nervous system disorders.
Figure 2
Figure 2
IR light activates TRPV channels by increasing the temperature.
Figure 3
Figure 3
The effect of IR light on the mitochondrial respiratory chain.
Figure 4
Figure 4
The overall structure of research on IR light regulation of neural function.

References

    1. Liu G., Zhou J., Li F. Functional Near-Infrared Spectroscopy: An Emerging Functional Neuroimaging Technology. J. Psychol. Sci. 2011;34:943–949.
    1. Cho S., Shin M.H., Kim Y.K., Seo J.E., Lee Y.M., Park C.H., Chung J.H. Effects of infrared radiation and heat on human skin aging in vivo. J. Investig. Dermatol. Symp. Proc. 2009;14:15–19. doi: 10.1038/jidsymp.2009.7. - DOI - PubMed
    1. Liu Y., Zhang H. Low-Level Laser Irradiation Precondition for Cardiac Regenerative Therapy. Photomed. Laser Surg. 2016;34:572–579. doi: 10.1089/pho.2015.4058. - DOI - PubMed
    1. Rojas J.C., Gonzalez-Lima F. Low-level light therapy of the eye and brain. Eye Brain. 2011;3:49–67. doi: 10.2147/eb.S21391. - DOI - PMC - PubMed
    1. Berman M.H., Nichols T.W. Treatment of Neurodegeneration: Integrating Photobiomodulation and Neurofeedback in Alzheimer’s Dementia and Parkinson’s: A Review. Photobiomodul Photomed. Laser Surg. 2019;37:623–634. doi: 10.1089/photob.2019.4685. - DOI - PubMed

LinkOut - more resources