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Review
. 2015 Oct-Dec;29(4):278-86.
doi: 10.1016/j.sjopt.2015.01.007. Epub 2015 Jan 24.

Advances in the treatment of central serous chorioretinopathy

Marwan A Abouammoh  1
Affiliations
Review

Advances in the treatment of central serous chorioretinopathy

Marwan A Abouammoh. Saudi J Ophthalmol. 2015 Oct-Dec.

Abstract

Central serous chorioretinopathy is a disease that is partly understood. Novel advancements have led to further understanding of the disease, and have identified choroidal dysfunction as the principal element in CSCR development. New imaging tools have aided in better monitoring disease response to various treatment models. Enhanced depth imaging optical coherence tomography, in particular, has helped in observing choroidal thickness changes after various treatment models. To date, photodynamic therapy and focal laser remain the main stay of treatment. More understanding of disease pathophysiology in the future will help in determining the drug of choice and the best management option for such cases.

Keywords: CSCR; Central serous chorioretinopathy; Central serous retinopathy; Corticosteroids; Photodynamic therapy; Treatment.

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Figures

Figure 1
Figure 1
Left eye of a 32-year-old man with chronic CSCR showing turbid subretinal fluid (top right). Fluorescein angiography shows pin-point leakage between the optic nerve and fovea (top left). Six months after focal laser photocoagulation to the leakage site shows resolution of the subretinal fluid with enlargement of the laser scar and some atrophic RPE changes (bottom right). Fluorescein angiography shows hypofluorescent area surrounded by a hyperfluorescent rim corresponding to the laser scar (bottom left). (Courtesy of Dr. Saba Al-Rashaed).
Figure 2
Figure 2
Left eye of a 48-year-old man with recurrent CSCR who was misdiagnosed as wet macular degeneration. Note the dull foveal reflex and RPE atrophic changes (top right). Fluorescein angiography shows diffuse irregular hyperfluorescence (top left). Optical coherence tomography shows shallow subretinal fluid reaching the fovea (Down).
Figure 3
Figure 3
Indocyanine green of the previous patient in Fig. 2 shows dilated/engorged choroidal vessels corresponding to the leakage seen on fluorescein angiography (top right). Late phase shows leakage from these choroidal vessels (top left). One month after half-dose photodynamic therapy the hypocyanescent area corresponds to the site of treatment (bottom right). It shows overall reduction in vascularity with decrease in choroidal vessel caliber. No more leakage can be seen on late phase of ICG (bottom left).
See this image and copyright information in PMC

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