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Mitosis Detection in Breast Cancer Histology Images with Deep Neural Networks

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Medical Image Computing and Computer-Assisted Intervention – MICCAI 2013 (MICCAI 2013)
Mitosis Detection in Breast Cancer Histology Images with Deep Neural Networks
  • Dan C. Cireşan21,
  • Alessandro Giusti21,
  • Luca M. Gambardella21 &
  • …
  • Jürgen Schmidhuber21 

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 8150))

Included in the following conference series:

  • International Conference on Medical Image Computing and Computer-Assisted Intervention
  • 23k Accesses

  • 1437 Citations

  • 31 Altmetric

Abstract

We use deep max-pooling convolutional neural networks to detect mitosis in breast histology images. The networks are trained to classify each pixel in the images, using as context a patch centered on the pixel. Simple postprocessing is then applied to the network output. Our approach won the ICPR 2012 mitosis detection competition, outperforming other contestants by a significant margin.

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Author information

Authors and Affiliations

  1. IDSIA, Dalle Molle Institute for Artificial Intelligence, USI-SUPSI, Lugano, Switzerland

    Dan C. Cireşan, Alessandro Giusti, Luca M. Gambardella & Jürgen Schmidhuber

Authors
  1. Dan C. Cireşan
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  2. Alessandro Giusti
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  3. Luca M. Gambardella
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  4. Jürgen Schmidhuber
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Editor information

Editors and Affiliations

  1. Information and Communications Headquarters,, Nagoya University, 464-8603, Nagoya, Japan

    Kensaku Mori

  2. Graduate School of Engineering,, University of Tokyo, 113-8656, Tokyo, Japan

    Ichiro Sakuma

  3. Graduate School of Medicine, Osaka University, 565-0871, Osaka, Japan

    Yoshinobu Sato

  4. IRISA, Campus Universitaire de Beaulieu, 35042, Rennes, France

    Christian Barillot

  5. Computer Aided Medical Procedures, Technical University of Munich, 85748, Garching, Germany

    Nassir Navab

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Cireşan, D.C., Giusti, A., Gambardella, L.M., Schmidhuber, J. (2013). Mitosis Detection in Breast Cancer Histology Images with Deep Neural Networks. In: Mori, K., Sakuma, I., Sato, Y., Barillot, C., Navab, N. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2013. MICCAI 2013. Lecture Notes in Computer Science, vol 8150. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40763-5_51

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  • DOI: https://doi.org/10.1007/978-3-642-40763-5_51

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Keywords

  • Ground Truth
  • Input Image
  • Convolutional Neural Network
  • Deep Neural Network
  • Mitotic Nucleus

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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